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While overall survival data are not yet available for the PALOMA 2 randomized controlled trial, these results expand our understanding of clinical outcomes in the real world setting and provide additional evidence regarding the use of palbociclib in combination with an aromatase inhibitor as a first line treatment of patients with HR HER2 MBC comprar lasix 59 61 Wade et al showed a 48 rate of ER expression and a 30 rate of PR expression